Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF94848.1PFAM: Domain of unknown function DUF512; PDZ/DHR/GLGF; KEGG: drm:Dred_1159 hypothetical protein. (436 aa)    
Predicted Functional Partners:
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
    0.816
AEF94849.1
KEGG: drm:Dred_1158 hypothetical protein.
       0.668
AEF94850.1
KEGG: drm:Dred_1157 hypothetical protein.
       0.638
gpsA
KEGG: drm:Dred_1162 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.586
plsY
Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
       0.584
AEF94852.1
PFAM: Protein of unknown function DUF1614; KEGG: drm:Dred_1155 Fis family transcriptional regulator.
       0.532
AEF94851.1
KEGG: drm:Dred_1156 stage II sporulation P family protein; TIGRFAM: Sporulation stage II, protein P; PFAM: Sporulation stage II, protein P.
       0.516
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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