STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF94859.1KEGG: drm:Dred_1148 aspartate aminotransferase; PFAM: Aminotransferase, class I/classII. (396 aa)    
Predicted Functional Partners:
AEF93412.1
KEGG: drm:Dred_2805 glutamate synthase (ferredoxin); PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
  
 
 0.959
AEF94857.1
Manually curated; KEGG: drm:Dred_1150 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
 
 0.934
AEF93832.1
PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; KEGG: dae:Dtox_0905 prephenate dehydratase; SMART: Chorismate mutase.
 
 
 0.929
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.919
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.919
hisC
PFAM: Aminotransferase, class I/classII; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: drm:Dred_2354 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.918
AEF93345.1
PFAM: GCN5-related N-acetyltransferase (GNAT) domain; KEGG: drm:Dred_2898 acetyltransferase; Belongs to the acetyltransferase family.
  
  
  0.917
argG
PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: drm:Dred_0277 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.916
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.910
AEF94135.1
Aspartate transaminase; KEGG: drm:Dred_1696 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII.
  
  
 
0.908
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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