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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEF95253.1PFAM: 4Fe-4S binding domain; KEGG: drm:Dred_0490 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (230 aa)    
Predicted Functional Partners:
AEF93853.1
Glutamate synthase (NADPH); KEGG: dal:Dalk_2523 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain.
 
 
 0.609
AEF94836.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: pth:PTH_1378 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
  
 
 0.488
AEF94893.1
NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S binding domain; KEGG: hmo:HM1_1744 proton-translocating NADH-ubiquinone oxidoreductase, chain F; SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
  
 
 0.488
AEF95252.1
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.482
AEF95149.1
PFAM: NapC/NirT cytochrome c, N-terminal; KEGG: drm:Dred_0700 cytochrome c nitrite reductase small subunit NrfH.
  
 
 0.466
AEF94583.1
PFAM: Pyrrolo-quinoline quinone repeat; KEGG: drm:Dred_2345 pyrrolo-quinoline quinone.
  
     0.452
Your Current Organism:
Desulfotomaculum nigrificans
NCBI taxonomy Id: 868595
Other names: D. nigrificans CO-1-SRB, Desulfotomaculum carboxydivorans CO-1-SRB, Desulfotomaculum carboxydivorans DSM 14880, Desulfotomaculum nigrificans CO-1-SRB
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