Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADY73706.1Roadblock/LC7 family protein; InterPro IPR004942; KEGG: gur:Gura_4331 roadblock/LC7 family protein; PFAM: Dynein light chain-related; SPTR: Roadblock/LC7 family protein; PFAM: Roadblock/LC7 domain. (157 aa)    
Predicted Functional Partners:
ADY73705.1
KEGG: ddf:DEFDS_0024 mutual gliding protein A; SPTR: Mutual gliding protein A; PFAM: Gtr1/RagA G protein conserved region; TIGRFAM: small GTP-binding protein domain.
 
 
 0.992
ADY74128.1
Miro domain protein; COGs: COG2229 GTPase; InterPro IPR013684; KEGG: aae:aq_1844 hypothetical protein; PFAM: MIRO-like; SPTR: Putative uncharacterized protein; PFAM: Miro-like protein.
  
 
 0.859
ADY73703.1
Protein of unknown function DUF218; COGs: COG1434 conserved hypothetical protein; InterPro IPR003848; KEGG: sul:SYO3AOP1_1020 protein of unknown function DUF218; PFAM: Protein of unknown function DUF218; SPTR: Putative uncharacterized protein; PFAM: DUF218 domain.
       0.773
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.773
ADY73707.1
COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: dth:DICTH_1986 PorB subunit of pyruvate:flavodoxin oxidoreductase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate synthase; SPTR: PorB subunit of pyruvate:flavodoxin oxidoreductase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
       0.773
recR
Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
       0.768
ADY73712.1
UPF0133 protein ybaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
       0.768
ADY73708.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: dtu:Dtur_0262 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: Pyruvate synthase; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain.
       0.762
ADY73709.1
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898; KEGG: kol:Kole_0380 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
       0.762
ADY73710.1
Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752: IPR011894; KEGG: tye:THEYE_A0907 pyruvate synthase subunit PorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Pyruvate synthase; SPTR: Pyruvate synthase subunit PorC; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2- [...]
       0.762
Your Current Organism:
Desulfurobacterium thermolithotrophum
NCBI taxonomy Id: 868864
Other names: D. thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum BSA, Desulfurobacterium thermolithotrophum DSM 11699, Desulfurobacterium thermolithotrophum str. DSM 11699, Desulfurobacterium thermolithotrophum strain DSM 11699
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