STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AEB10832.1KEGG: msv:Mesil_2944 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504659636; PFAM: Outer membrane efflux protein. (427 aa)    
Predicted Functional Partners:
Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: tth:TTC0378 hypothetical protein; PFAM: Secretion protein HlyD; SPTR: Hypothetical membrane spanning protein; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504660636; PFAM: HlyD family secretion protein.
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: tth:TTC0377 acriflavin resistance protein B; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; IMG reference gene:2504660637; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
Transcriptional repressor nrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: msv:Mesil_0043 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; manually curated; IMG reference gene:2504659638; PFAM: short chain dehydrogenase.
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: opr:Ocepr_2161 undecaprenyl-phosphate galactose phosphotransferase, wbap; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504661437; [...]
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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