STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB10842.1Uncharacterized protein family UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (406 aa)    
Predicted Functional Partners:
AEB10843.1
UPF0042 nucleotide-binding protein yhbJ; Displays ATPase and GTPase activities.
  
  
 0.945
AEB10841.1
Protein of unknown function DUF2223; COGs: COG4945 Membrane-anchored protein predicted to be involved in regulation of amylopullulanase; InterPro IPR019248; KEGG: opr:Ocepr_0259 hypothetical protein; PFAM: Domain of unknown function DUF2223; SPTR: Membrane-anchored protein predicted to be involved in regulation of amylopullulanase; IMG reference gene:2504659645; PFAM: Domain of unknown function (DUF2223).
       0.810
AEB10840.1
KEGG: opr:Ocepr_0257 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504659644.
 
     0.802
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
       0.653
AEB10844.1
Mannosyl-3-phosphoglycerate phosphatase; COGs: COG3769 hydrolase (HAD superfamily); InterPro IPR006379:IPR006381:IPR012813:IPR013200; KEGG: rmr:Rmar_0501 mannosyl-3-phosphoglycerate phosphatase; PFAM: HAD superfamily hydrolase-like, type 3; PRIAM: Mannosyl-3-phosphoglycerate phosphatase; SPTR: Mannosyl-3-phosphoglycerate phosphatase; TIGRFAM: Mannosyl-3-phosphoglycerate phosphatase; HAD-superfamily hydrolase, superfamily IIB, YedP; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504659648; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: mannosyl-3-phosphoglycerate ph [...]
       0.641
AEB10845.1
InterPro IPR012812; KEGG: ttj:TTHA0954 mannosyl-3-phosphoglycerate synthase; PFAM: Mannosyl-3-phosphoglycerate synthase; PRIAM: Mannosyl-3-phosphoglycerate synthase; SPTR: Mannosyl-3-phosphoglycerate synthase; TIGRFAM: Mannosyl-3-phosphoglycerate synthase; IMG reference gene:2504659649; PFAM: Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth); TIGRFAM: mannosyl-3-phosphoglycerate synthase.
       0.641
AEB11577.1
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932:IPR014045; KEGG: opr:Ocepr_1649 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; IMG reference gene:2504660419; PFAM: Protein phosphatase 2C.
  
  
 0.641
AEB11078.1
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR010822:IPR001932; KEGG: opr:Ocepr_0504 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C, N-terminal; Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein serine/threonine phosphatase; IMG reference gene:2504659897; PFAM: Protein phosphatase 2C.
  
  
 0.625
AEB10846.1
Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: opr:Ocepr_0251 hypothetical protein; PFAM: Protein of unknown function DUF156; SPTR: Hypothetical cytosolic protein; IMG reference gene:2504659650; PFAM: Uncharacterised BCR, COG1937.
       0.587
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.574
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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