STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB10919.1Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: opr:Ocepr_0249 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Small heat shock protein; IMG reference gene:2504659726; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. (138 aa)    
Predicted Functional Partners:
AEB10920.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tth:TTC1116 small heat shock protein; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; IMG reference gene:2504659727; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
 
     0.923
AEB12132.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: opr:Ocepr_0921 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; IMG reference gene:2504660996; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
  
     0.775
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.636
AEB12113.1
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176:IPR003959:IPR013093:IPR019489:IPR 003593; KEGG: msv:Mesil_2175 ATPase AAA-2 domain protein; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATPase AAA-2 domain protein; manually curated; IMG reference gene:2504660977; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); Belongs to [...]
  
 
 0.634
AEB10921.1
TrkA-C domain protein; COGs: COG0490 Putative regulatory ligand-binding protein related to C-terminal domains of K+ channels; InterPro IPR006037; KEGG: msv:Mesil_0407 TrkA-C domain protein; PFAM: Regulator of K+ conductance, C-terminal; SPTR: TrkA-C domain protein; IMG reference gene:2504659728; PFAM: TrkA-C domain.
       0.620
AEB10922.1
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: ttj:TTHA1476 Na(+)/H(+) antiporter; PFAM: Cation/H+ exchanger; SPTR: Putative uncharacterized protein; IMG reference gene:2504659729; PFAM: Sodium/hydrogen exchanger family.
     
 0.617
AEB10923.1
Hypothetical protein; IMG reference gene:2504659730.
       0.612
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.559
AEB10924.1
Protein of unknown function DUF114; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002825; KEGG: ttj:TTHA1475 hypothetical protein; PFAM: Peptidase S49, serine-peptidase prokaryotes; SPTR: Putative uncharacterized protein TTHA1475; IMG reference gene:2504659731; PFAM: Serine dehydrogenase proteinase.
     
 0.491
apgM
Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.453
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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