STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB10922.1Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: ttj:TTHA1476 Na(+)/H(+) antiporter; PFAM: Cation/H+ exchanger; SPTR: Putative uncharacterized protein; IMG reference gene:2504659729; PFAM: Sodium/hydrogen exchanger family. (378 aa)    
Predicted Functional Partners:
AEB10921.1
TrkA-C domain protein; COGs: COG0490 Putative regulatory ligand-binding protein related to C-terminal domains of K+ channels; InterPro IPR006037; KEGG: msv:Mesil_0407 TrkA-C domain protein; PFAM: Regulator of K+ conductance, C-terminal; SPTR: TrkA-C domain protein; IMG reference gene:2504659728; PFAM: TrkA-C domain.
 
  
 0.964
AEB10923.1
Hypothetical protein; IMG reference gene:2504659730.
       0.773
AEB10920.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tth:TTC1116 small heat shock protein; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; IMG reference gene:2504659727; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
     
 0.700
AEB10919.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: opr:Ocepr_0249 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Small heat shock protein; IMG reference gene:2504659726; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
     
 0.617
AEB12086.1
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148; KEGG: msv:Mesil_2255 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504660947; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
0.614
AEB10924.1
Protein of unknown function DUF114; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002825; KEGG: ttj:TTHA1475 hypothetical protein; PFAM: Peptidase S49, serine-peptidase prokaryotes; SPTR: Putative uncharacterized protein TTHA1475; IMG reference gene:2504659731; PFAM: Serine dehydrogenase proteinase.
       0.576
AEB11284.1
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153:IPR003148; KEGG: opr:Ocepr_0024 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504660118; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
   
 
 0.523
AEB11889.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: opr:Ocepr_1185 cl-channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Probable voltage gated chloride channel; IMG reference gene:2504660739; PFAM: Voltage gated chloride channel; TrkA-C domain.
     
 0.422
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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