STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEB10926.12-methylcitrate dehydratase; COGs: COG2079 Uncharacterized protein involved in propionate catabolism; InterPro IPR005656; KEGG: vdi:Vdis_1889 2-methylcitrate dehydratase; PFAM: MmgE/PrpD; PRIAM: 2-methylcitrate dehydratase; SPTR: 2-methylcitrate dehydratase; IMG reference gene:2504659733; PFAM: MmgE/PrpD family. (459 aa)    
Predicted Functional Partners:
AEB10925.1
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
 
  
 0.991
AEB11811.1
2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR011278:IPR002020; KEGG: opr:Ocepr_0974 citrate synthase; PFAM: Citrate synthase-like; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; IMG reference gene:2504660660; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 0.908
AEB10929.1
COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: opr:Ocepr_0061 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504659736; PFAM: Tripartite tricarboxylate transporter family receptor.
  
    0.794
AEB10927.1
Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: msv:Mesil_0732 protein of unknown function DUF112 transmembrane; PFAM: Protein of unknown function DUF112, transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504659734; PFAM: Tripartite tricarboxylate transporter TctA family.
       0.791
AEB10928.1
KEGG: mrb:Mrub_2823 putative tricarboxylic transport membrane protein; SPTR: Putative tricarboxylic transport membrane protein; IMG reference gene:2504659735; PFAM: Tripartite tricarboxylate transporter TctB family.
       0.789
AEB11662.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: ttj:TTHA1557 propionyl-CoA carboxylase, beta subunit; PFAM: Carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase, beta subunit; IMG reference gene:2504660505; PFAM: Carboxyl transferase domain.
  
    0.511
AEB12382.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: opr:Ocepr_1726 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase, alpha subunit; IMG reference gene:2504661256; PFAM: Carboxyl transferase domain.
  
    0.511
AEB10930.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: mrb:Mrub_1754 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein; IMG reference gene:2504659737; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
       0.454
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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