node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB10995.1 | AEB10997.1 | Marky_0234 | Marky_0236 | Peptidase M28; InterPro IPR007484; KEGG: opr:Ocepr_0450 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504659805; PFAM: Peptidase family M28. | Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR003593:IPR001482; KEGG: opr:Ocepr_0453 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Pili retraction protein pilT; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504659807; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. | 0.639 |
AEB10995.1 | guaB | Marky_0234 | Marky_0232 | Peptidase M28; InterPro IPR007484; KEGG: opr:Ocepr_0450 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504659805; PFAM: Peptidase family M28. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.503 |
AEB10995.1 | panC | Marky_0234 | Marky_0235 | Peptidase M28; InterPro IPR007484; KEGG: opr:Ocepr_0450 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504659805; PFAM: Peptidase family M28. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.639 |
AEB10997.1 | AEB10995.1 | Marky_0236 | Marky_0234 | Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR003593:IPR001482; KEGG: opr:Ocepr_0453 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Pili retraction protein pilT; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504659807; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. | Peptidase M28; InterPro IPR007484; KEGG: opr:Ocepr_0450 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504659805; PFAM: Peptidase family M28. | 0.639 |
AEB10997.1 | panC | Marky_0236 | Marky_0235 | Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR003593:IPR001482; KEGG: opr:Ocepr_0453 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Pili retraction protein pilT; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504659807; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.810 |
AEB11250.1 | panB | Marky_0498 | Marky_0497 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.993 |
AEB11250.1 | panC | Marky_0498 | Marky_0235 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.936 |
AEB11822.1 | panC | Marky_1080 | Marky_0235 | COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814; KEGG: opr:Ocepr_0978 4-aminobutyrate aminotransferase apoenzyme; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; IMG reference gene:2504660671; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.904 |
AEB11822.1 | panD | Marky_1080 | Marky_1339 | COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR005814; KEGG: opr:Ocepr_0978 4-aminobutyrate aminotransferase apoenzyme; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; IMG reference gene:2504660671; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.913 |
AEB12357.1 | coaX | Marky_1622 | Marky_1890 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.928 |
AEB12357.1 | panB | Marky_1622 | Marky_0497 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.492 |
AEB12357.1 | panC | Marky_1622 | Marky_0235 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.872 |
cmk | guaB | Marky_0674 | Marky_0232 | COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: opr:Ocepr_1777 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504660262; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.481 |
cmk | panC | Marky_0674 | Marky_0235 | COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: opr:Ocepr_1777 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504660262; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.907 |
coaX | AEB12357.1 | Marky_1890 | Marky_1622 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.928 |
coaX | panC | Marky_1890 | Marky_0235 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.971 |
coaX | panD | Marky_1890 | Marky_1339 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.879 |
guaB | AEB10995.1 | Marky_0232 | Marky_0234 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Peptidase M28; InterPro IPR007484; KEGG: opr:Ocepr_0450 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28; IMG reference gene:2504659805; PFAM: Peptidase family M28. | 0.503 |
guaB | cmk | Marky_0232 | Marky_0674 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: opr:Ocepr_1777 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504660262; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. | 0.481 |
guaB | panC | Marky_0232 | Marky_0235 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.608 |