STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11029.1COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: opr:Ocepr_0543 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504659840; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (381 aa)    
Predicted Functional Partners:
AEB11028.1
Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR003607:IPR006674; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: Conserved hypothetical protein CHP00488; IMG reference gene:2504659839; PFAM: HD domain; TIGRFAM: putative HD superfamily hydrolase of NAD metabolism.
 
    0.863
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.815
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.810
obg
GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.805
rpmA
COGs: COG0211 Ribosomal protein L27; HAMAP: Ribosomal protein L27; InterPro IPR001684; KEGG: tth:TTC1423 50S ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; IMG reference gene:2504659836; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
       0.790
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.781
AEB11031.1
UPF0102 protein yraN; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; HAMAP: Uncharacterised protein family UPF0102; InterPro IPR003509; KEGG: msv:Mesil_0358 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein Mesil_0358; TIGRFAM: Uncharacterised protein family UPF0102; IMG reference gene:2504659842; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family.
       0.780
AEB11032.1
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153; KEGG: opr:Ocepr_1884 sodium/proton antiporter, cpa1 family; PFAM: Cation/H+ exchanger; SPTR: Na+/H+ antiporter; IMG reference gene:2504659843; PFAM: Sodium/hydrogen exchanger family.
     
 0.734
AEB11715.1
Polysaccharide pyruvyl transferase CsaB; COGs: COG2327 conserved hypothetical protein; InterPro IPR019896:IPR007345; KEGG: msv:Mesil_2202 polysaccharide pyruvyl transferase CsaB; PFAM: Polysaccharide pyruvyl transferase; SPTR: Polysaccharide pyruvyl transferase CsaB; TIGRFAM: Polysaccharide pyruvyl transferase, CsaB; IMG reference gene:2504660560; PFAM: Polysaccharide pyruvyl transferase; TIGRFAM: polysaccharide pyruvyl transferase CsaB.
 
     0.720
AEB11033.1
Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: msv:Mesil_0356 UbiD family decarboxylase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504659844; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases; Belongs to the UbiD family.
       0.710
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.