STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB11144.1Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: opr:Ocepr_1922 cation transporter; PFAM: Cation transporter; SPTR: Cation transporter; IMG reference gene:2504659967; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family. (482 aa)    
Predicted Functional Partners:
AEB11143.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: opr:Ocepr_1921 TrkA-n domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: TrkA-N domain protein; IMG reference gene:2504659966; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.988
AEB11284.1
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153:IPR003148; KEGG: opr:Ocepr_0024 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504660118; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
 
 0.926
AEB11889.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: opr:Ocepr_1185 cl-channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Probable voltage gated chloride channel; IMG reference gene:2504660739; PFAM: Voltage gated chloride channel; TrkA-C domain.
 
 
 0.894
AEB12086.1
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153:IPR003148; KEGG: msv:Mesil_2255 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504660947; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.859
rimO
Ribosomal protein S12 methylthiotransferase rimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
  
 0.794
AEB11141.1
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; InterPro IPR013229:IPR001387; KEGG: opr:Ocepr_1919 pega domain protein; PFAM: PEGA; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504659964; PFAM: PEGA domain.
  
    0.633
psuG
Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
       0.551
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.457
AEB11033.1
Menaquinone biosynthesis decarboxylase, SCO4490 family; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: msv:Mesil_0356 UbiD family decarboxylase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504659844; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: menaquinone biosynthesis decarboxylase, SCO4490 family; UbiD family decarboxylases; Belongs to the UbiD family.
      0.421
AEB11139.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: mrb:Mrub_2968 Rossmann fold nucleotide-binding protein; PFAM: Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG; SPTR: Rossmann fold nucleotide-binding protein; IMG reference gene:2504659962; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein.
       0.412
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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