STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11154.1Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR011717:IPR001440:IPR019734; KEGG: mrb:Mrub_2483 tetratricopeptide TPR_4; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; SPTR: Tetratricopeptide TPR_4; IMG reference gene:2504659978. (452 aa)    
Predicted Functional Partners:
AEB11487.1
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: msv:Mesil_2938 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2; IMG reference gene:2504660325; PFAM: Glycosyl transferase family 2.
  
 
 0.766
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.753
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.751
AEB12811.1
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: tpe:Tpen_1284 ankyrin; PFAM: Ankyrin repeat; SPTR: Ankyrin; IMG reference gene:2504661705; PFAM: Ankyrin repeat.
   
 0.733
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.654
AEB11101.1
WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR019781:IPR001680; KEGG: ssl:SS1G_05532 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD-repeat protein, putative; IMG reference gene:2504659921; PFAM: WD domain, G-beta repeat; PEGA domain.
   
 0.610
AEB12748.1
WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR019781; KEGG: scl:sce2686 WD repeat-containing protein; PFAM: WD40 repeat, subgroup; SPTR: Hypothetical WD-repeat protein; IMG reference gene:2504661635; PFAM: WD domain, G-beta repeat.
   
 0.610
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.587
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  0.580
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.577
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.