STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11222.1Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: opr:Ocepr_0654 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504660054; PFAM: N-acetylmuramoyl-L-alanine amidase. (378 aa)    
Predicted Functional Partners:
AEB11953.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: opr:Ocepr_1134 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin; IMG reference gene:2504660807; PFAM: N-acetylmuramoyl-L-alanine amidase.
  
  
 
0.929
AEB11216.1
Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: opr:Ocepr_0648 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative transpeptidase, cell division protein ftsI; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504660048; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-b [...]
 
  
 0.834
AEB11218.1
COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: opr:Ocepr_0650 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; IMG reference gene:2504660050; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC.
 
  
 0.831
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
       0.781
minC
Septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
     
 0.780
AEB11219.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.780
AEB11217.1
KEGG: opr:Ocepr_0649 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; IMG reference gene:2504660049; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD.
       0.773
AEB11220.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ttj:TTHA1187 hypothetical protein; PFAM: Phospholipase D/Transphosphatidylase; SMART: Phospholipase D/Transphosphatidylase; SPTR: Putative uncharacterized protein TTHA1187; IMG reference gene:2504660052.
       0.773
AEB10857.1
Peptidase S54, rhomboid domain protein; COGs: COG0705 membrane protein; InterPro IPR022764; KEGG: ttj:TTHA1474 hypothetical protein; PFAM: Peptidase S54, rhomboid domain; SPTR: Hypothetical membrane spanning protein; IMG reference gene:2504659661; PFAM: Rhomboid family.
  
   0.715
AEB11225.1
Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: msv:Mesil_1407 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Permease YjgP/YjgQ family protein; IMG reference gene:2504660057; PFAM: Predicted permease YjgP/YjgQ family.
 
     0.621
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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