node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB10934.1 | AEB11242.1 | Marky_0171 | Marky_0490 | ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...] | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | 0.540 |
AEB10934.1 | cobB | Marky_0171 | Marky_0485 | ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...] | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | 0.838 |
AEB11240.1 | AEB11241.1 | Marky_0488 | Marky_0489 | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | 0.697 |
AEB11240.1 | AEB11242.1 | Marky_0488 | Marky_0490 | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | 0.697 |
AEB11240.1 | cobB | Marky_0488 | Marky_0485 | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | 0.553 |
AEB11240.1 | nnrE | Marky_0488 | Marky_0486 | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.823 |
AEB11240.1 | thrB | Marky_0488 | Marky_0487 | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.780 |
AEB11241.1 | AEB11240.1 | Marky_0489 | Marky_0488 | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | 0.697 |
AEB11241.1 | AEB11242.1 | Marky_0489 | Marky_0490 | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | 0.780 |
AEB11241.1 | cobB | Marky_0489 | Marky_0485 | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | 0.536 |
AEB11241.1 | nnrE | Marky_0489 | Marky_0486 | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.683 |
AEB11241.1 | thrB | Marky_0489 | Marky_0487 | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.697 |
AEB11242.1 | AEB10934.1 | Marky_0490 | Marky_0171 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...] | 0.540 |
AEB11242.1 | AEB11240.1 | Marky_0490 | Marky_0488 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | 0.697 |
AEB11242.1 | AEB11241.1 | Marky_0490 | Marky_0489 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | Regulatory protein TetR; InterPro IPR001647; KEGG: opr:Ocepr_1495 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504660073; PFAM: Bacterial regulatory proteins, tetR family. | 0.780 |
AEB11242.1 | cobB | Marky_0490 | Marky_0485 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | 0.524 |
AEB11242.1 | nnrE | Marky_0490 | Marky_0486 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.724 |
AEB11242.1 | thrB | Marky_0490 | Marky_0487 | methylated-DNA/protein- cysteinemethyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: ttj:TTHA1564 putative methylated-DNA--protein-cysteine methyltransferase (Ogt); PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Putative methylated-DNA--protein-cysteine methyltransferase (Ogt); TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504660074; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.706 |
cobB | AEB10934.1 | Marky_0485 | Marky_0171 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...] | 0.838 |
cobB | AEB11240.1 | Marky_0485 | Marky_0488 | COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: Silent information regulator protein Sir2; IMG reference gene:2504660069; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily. | KEGG: mrb:Mrub_2051 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660072. | 0.553 |