STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11272.1COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR006091:IPR006090; KEGG: opr:Ocepr_0750 butyryl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Acyl-CoA dehydrogenase domain protein; IMG reference gene:2504660104; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (381 aa)    
Predicted Functional Partners:
AEB12381.1
COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: opr:Ocepr_1723 electron transfer flavoprotein alpha subunit; PFAM: Electron transfer flavoprotein, alpha subunit, C-terminal; Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha subunit; IMG reference gene:2504661255; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain.
 
 0.991
AEB12380.1
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: opr:Ocepr_1722 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein alpha/beta-subunit; IMG reference gene:2504661254; PFAM: Electron transfer flavoprotein domain.
 
 
 0.905
AEB12122.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753; KEGG: opr:Ocepr_0933 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; Crotonase, core; SPTR: Putative 3-hydroxyacyl-CoA dehydrogenase; IMG reference gene:2504660986; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.878
AEB11271.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: opr:Ocepr_1451 radical sam domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein nirJ; IMG reference gene:2504660103; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain; radical SAM protein, BA_1875 family.
  
    0.654
AEB11273.1
COGs: COG1485 ATPase; InterPro IPR005654; KEGG: ttj:TTHA0326 putative ATP/GTP-binding integral membrane protein; PFAM: ATPase, AFG1-like; SPTR: Putative ATP/GTP-binding integral membrane protein; IMG reference gene:2504660105; PFAM: AFG1-like ATPase.
       0.651
AEB11625.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: msv:Mesil_1466 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA dehydrogenase; SPTR: 3-hydroxybutyryl-CoA dehydrogenase; IMG reference gene:2504660468; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 0.609
AEB11270.1
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099; KEGG: opr:Ocepr_2051 fad-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SPTR: NADH oxidase; IMG reference gene:2504660102; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
 
 0.566
nuoI
NAD(P)H-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 0.553
AEB12007.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: msv:Mesil_2315 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; PRIAM: 3-hydroxybutyryl-CoA dehydrogenase; SPTR: 3-hydroxybutyryl-CoA dehydrogenase; manually curated; IMG reference gene:2504660861; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 
 0.547
AEB10806.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR020616:IPR020617; KEGG: tth:TTC0330 acetyl-CoA acetyltransferase; PFAM: Thiolase, N-terminal; Thiolase, C-terminal; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; IMG reference gene:2504659604; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.539
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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