STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11284.1Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006153:IPR003148; KEGG: opr:Ocepr_0024 sodium/hydrogen exchanger; PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; SPTR: Sodium/hydrogen exchanger; IMG reference gene:2504660118; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (617 aa)    
Predicted Functional Partners:
AEB11144.1
Cation transporter; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: opr:Ocepr_1922 cation transporter; PFAM: Cation transporter; SPTR: Cation transporter; IMG reference gene:2504659967; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family.
 
 
 0.926
AEB11285.1
KEGG: opr:Ocepr_0025 hypothetical protein; SPTR: Putative uncharacterized protein TTHA1662; IMG reference gene:2504660119.
       0.752
AEB11286.1
Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198; KEGG: pfu:PF0074 alcohol dehydrogenase, short chain; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Alcohol dehydrogenase, short chain; IMG reference gene:2504660120; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.622
AEB11889.1
Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: opr:Ocepr_1185 cl-channel voltage-gated family protein; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Probable voltage gated chloride channel; IMG reference gene:2504660739; PFAM: Voltage gated chloride channel; TrkA-C domain.
 
  
 0.607
AEB11167.1
COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: ttj:TTHA1715 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: Putative uncharacterized protein TTHA1715; IMG reference gene:2504659993; PFAM: Mechanosensitive ion channel.
 
   
 0.594
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
    0.561
AEB11062.1
COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR010034:IPR010038:IPR003749:IPR003448; KEGG: tth:TTC1947 molybdopterin (MPT) converting factor, subunit 2; PFAM: Molybdopterin biosynthesis MoaE; ThiamineS; SPTR: Molybdopterin converting factor, subunit 1; TIGRFAM: Molybdopterin converting factor, subunit 1; MoaD, archaeal; IMG reference gene:2504659879; PFAM: ThiS family; MoaE protein; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.
  
    0.551
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.535
AEB10922.1
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: ttj:TTHA1476 Na(+)/H(+) antiporter; PFAM: Cation/H+ exchanger; SPTR: Putative uncharacterized protein; IMG reference gene:2504659729; PFAM: Sodium/hydrogen exchanger family.
   
 
 0.523
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.523
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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