STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AEB11325.1COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: mrb:Mrub_0792 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: NADH dehydrogenase (ubiquinone); SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; IMG reference gene:2504660160; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (430 aa)    
Predicted Functional Partners:
Peptidylprolyl isomerase; COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: opr:Ocepr_0599 peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504660223; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR001440:IPR008258; KEGG: ttj:TTHA1471 putative transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; Tetratricopeptide TPR-1; SPTR: Putative uncharacterized protein; IMG reference gene:2504660161; PFAM: Transglycosylase SLT domain.
COGs: COG0843 Heme/copper-type cytochrome/quinol oxidase subunit 1; InterPro IPR014241:IPR000883:IPR000298; KEGG: msv:Mesil_0629 cytochrome c oxidase, subunit I; PFAM: Cytochrome c oxidase, subunit I; Cytochrome c oxidase, subunit III; SPTR: Cytochrome c oxidase, subunit I; TIGRFAM: Cytochrome c oxidase, subunit I bacterial type; IMG reference gene:2504661575; PFAM: Cytochrome c oxidase subunit III; Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family.
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
Rieske (2Fe-2S) iron-sulfur domain protein; COGs: COG0723 Rieske Fe-S protein; InterPro IPR017941:IPR006311; KEGG: opr:Ocepr_0103 rieske (2Fe-2S) iron-sulfur domain; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: Rieske iron-sulfur protein; IMG reference gene:2504661800; PFAM: Rieske [2Fe-2S] domain.
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: tra:Trad_0209 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); IMG reference gene:2504660877; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR022367:IPR002880; KEGG: ttj:TTHA1955 2-oxoacid--ferredoxin oxidoreductase, alpha chain; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoacid--ferredoxin oxidoreductase, alpha chain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; IMG reference gene:2504660285; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:accept [...]
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Molybdopterin oxidoreductase, iron-sulfur binding subunit; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311; KEGG: noc:Noc_1238 molybdopterin oxidoreductase, iron-sulfur binding subunit; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit; IMG reference gene:2504661810.
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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