STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11497.1RNA methylase, NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR011023:IPR001678; KEGG: opr:Ocepr_1569 fmu (sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: RNA methylase, NOL1/NOP2/sun family; TIGRFAM: Nop2p; IMG reference gene:2504660335; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase. (450 aa)    
Predicted Functional Partners:
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
  
 0.828
AEB10892.1
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545:IPR012562; KEGG: opr:Ocepr_0322 ATP-dependent RNA helicase DbpA; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; GUCT; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase domain protein; IMG reference gene:2504659698; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 
 0.811
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.793
AEB11498.1
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: mrb:Mrub_2496 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2504660336; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
       0.780
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.766
rpmD
COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR016082:IPR005996; KEGG: opr:Ocepr_1610 LSU ribosomal protein l30p; PFAM: Ribosomal protein L30, ferredoxin-like fold domain; SPTR: 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; IMG reference gene:2504661317; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
   
 
 0.765
rplW
Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
 
 0.758
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.752
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.750
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
   0.750
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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