STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11511.1Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: opr:Ocepr_1556 peptidase S1 and S6 chymotrypsin/hap; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: PDZ/DHR/GLGF domain protein; IMG reference gene:2504660349; PFAM: Trypsin. (355 aa)    
Predicted Functional Partners:
AEB11510.1
COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: msv:Mesil_2453 deoxynucleoside kinase; PFAM: Deoxynucleoside kinase; SPTR: Deoxynucleoside kinase; IMG reference gene:2504660348; PFAM: Deoxynucleoside kinase.
       0.805
AEB11509.1
COGs: COG1428 Deoxynucleoside kinase; InterPro IPR001977:IPR002624; KEGG: opr:Ocepr_1558 deoxynucleoside kinase; PFAM: Deoxynucleoside kinase; Dephospho-CoA kinase; PRIAM: Deoxyadenosine kinase; SPTR: Deoxynucleoside kinase; IMG reference gene:2504660347; PFAM: Deoxynucleoside kinase.
       0.783
argS
COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR008909:IPR005148:IPR015945; KEGG: opr:Ocepr_1555 arginyl-tRNA synthetase; PFAM: DALR anticodon binding; Arginyl tRNA synthetase, class Ic, N-terminal; Arginyl-tRNA synthetase, class Ic, core; PRIAM: Arginine--tRNA ligase; SMART: DALR anticodon binding; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; IMG reference gene:2504660350; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRN [...]
  
  
 0.753
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.735
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.643
AEB11809.1
Mov34/MPN/PAD-1 family protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: opr:Ocepr_0972 mov34/mpn/pad-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1; SPTR: Metal-dependent protease of the PAD1/JAB1 superfamily; IMG reference gene:2504660658; PFAM: Mov34/MPN/PAD-1 family.
   
  0.558
AEB11514.1
KEGG: mrb:Mrub_2396 NADH dehydrogenase (quinone); PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); IMG reference gene:2504660352; PFAM: NADH-quinone oxidoreductase chain 15.
       0.534
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.491
AEB12871.1
MaoC domain protein dehydratase; COGs: COG2030 Acyl dehydratase; InterPro IPR002539; KEGG: mrb:Mrub_1674 MaoC domain-containing protein dehydratase; PFAM: MaoC-like dehydratase; SPTR: MaoC domain protein dehydratase; IMG reference gene:2504661768; PFAM: MaoC like domain.
    
  0.486
AEB10775.1
PspC domain protein; InterPro IPR007168; KEGG: mtt:Ftrac_1338 phage shock protein C, PspC; PFAM: Phage shock domain; SPTR: PspC domain protein; IMG reference gene:2504659573; PFAM: PspC domain.
  
  
 0.474
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.