STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11636.1COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR011717; KEGG: opr:Ocepr_0833 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Tetratricopeptide TPR-4; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Putative adenylate/guanylate cyclase; IMG reference gene:2504660479; PFAM: Adenylate and Guanylate cyclase catalytic domain. (1055 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.818
AEB11552.1
InterPro IPR019734:IPR013105:IPR001440; KEGG: opr:Ocepr_1672 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504660394; PFAM: Tetratricopeptide repeat.
 
 
 
 0.813
AEB11637.1
KEGG: opr:Ocepr_0834 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660480.
       0.805
AEB11666.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: mrb:Mrub_2129 Crp/Fnr family transcriptional regulator; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504660509; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
 
 0.784
AEB11673.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: opr:Ocepr_0789 transcriptional regulator, crp/fnr family; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504660518; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
 
 0.735
AEB10866.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: msv:Mesil_2833 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504659670; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
 
 0.734
AEB11763.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001808:IPR000595; KEGG: msv:Mesil_2484 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SMART: HTH transcriptional regulator, Crp; SPTR: Transcriptional regulator, Crp/Fnr family; IMG reference gene:2504660609; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
 0.694
AEB12569.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR001808; KEGG: msv:Mesil_0258 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; HTH transcriptional regulator, Crp; SPTR: Denitrification regulator T; IMG reference gene:2504661450; PFAM: Cyclic nucleotide-binding domain.
  
 0.694
AEB12822.1
KEGG: opr:Ocepr_0211 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504661716.
  
     0.685
AEB12027.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR013655:IPR013767:IPR003018:IPR000160:IPR 001633:IPR000014:IPR001610; KEGG: aae:aq_1442 hypothetical protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; PAS fold-3; PAS fold; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; PAS; PAC motif; SPTR: Putative uncharacterized protein; TIGRFAM: PAS; Diguanylate cyclase, predicted; IMG ref [...]
  
 
 0.666
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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