STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11689.1Transketolase; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: aau:AAur_3583 putative transketolase subunit A; PFAM: Transketolase, N-terminal; PRIAM: Transketolase; SPTR: Putative transketolase subunit A; IMG reference gene:2504660534; PFAM: Transketolase, thiamine diphosphate binding domain. (287 aa)    
Predicted Functional Partners:
AEB11688.1
1-deoxy-D-xylulose-5-phosphate synthase; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: ttr:Tter_1527 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase central region; IMG reference gene:2504660533; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 0.999
AEB11665.1
COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: opr:Ocepr_0783 ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504660508; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase.
 
 0.997
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
 
  
 0.932
AEB11562.1
Transketolase; COGs: COG0021 Transketolase; InterPro IPR005478:IPR005475:IPR005474:IPR005476; KEGG: opr:Ocepr_1662 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; TIGRFAM: Transketolase, bacterial-like; IMG reference gene:2504660404; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and ye [...]
 
  
 
0.917
AEB12213.1
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: opr:Ocepr_1301 fructose-1,6-bisphosphatase, class II; PFAM: Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase, class II; TIGRFAM: Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; IMG reference gene:2504661081; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
 
   
  0.913
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.907
AEB11400.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: msv:Mesil_2615 PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein; IMG reference gene:2504660237; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.906
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: mrb:Mrub_2801 phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504661569; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
     
 0.906
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.904
AEB11148.1
Ribose-phosphate pyrophosphokinase; COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: opr:Ocepr_1939 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504659971; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase.
    
  0.903
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.