STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB11691.1Myo-inosose-2 dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ttr:Tter_1521 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Myo-inosose-2 dehydratase; SPTR: Xylose isomerase domain protein TIM barrel; IMG reference gene:2504660536; PFAM: Xylose isomerase-like TIM barrel. (291 aa)    
Predicted Functional Partners:
AEB11692.1
COGs: COG3962 Acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766; KEGG: mrb:Mrub_1695 thiamine pyrophosphate protein central region; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Thiamine pyrophosphate protein central region; IMG reference gene:2504660537; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP bin [...]
 
 0.998
AEB11687.1
Inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: mrb:Mrub_1699 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Inositol 2-dehydrogenase; SPTR: Oxidoreductase domain protein; IMG reference gene:2504660532; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
 
 0.997
AEB11693.1
Inositol 2-dehydrogenase; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: mrb:Mrub_1694 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Inositol 2-dehydrogenase; SPTR: Oxidoreductase domain protein; IMG reference gene:2504660538; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
 
 0.997
AEB11686.1
Myo-inositol catabolism IolB domain protein; COGs: COG3718 Uncharacterized protein involved in inositol metabolism; KEGG: msv:Mesil_0995 myo-inositol catabolism IolB domain protein; SPTR: Myo-inositol catabolism IolB domain protein; IMG reference gene:2504660531; PFAM: KduI/IolB family.
  
 0.991
AEB11689.1
Transketolase; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: aau:AAur_3583 putative transketolase subunit A; PFAM: Transketolase, N-terminal; PRIAM: Transketolase; SPTR: Putative transketolase subunit A; IMG reference gene:2504660534; PFAM: Transketolase, thiamine diphosphate binding domain.
       0.782
AEB11688.1
1-deoxy-D-xylulose-5-phosphate synthase; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: ttr:Tter_1527 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase central region; IMG reference gene:2504660533; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
       0.781
AEB11690.1
Tartrate dehydrogenase; COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR011829:IPR001804; KEGG: rsk:RSKD131_4374 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Tartrate decarboxylase; SPTR: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: Tartrate dehydrogenase; IMG reference gene:2504660535; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: tartrate dehydrogenase.
       0.773
AEB11685.1
Transcriptional regulator, DeoR family; COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: mrb:Mrub_1701 DeoR family transcriptional regulator; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504660530; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain.
  
  
 0.772
AEB10930.1
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: mrb:Mrub_1754 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein; IMG reference gene:2504659737; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
 
  
 0.767
AEB12654.1
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: mrb:Mrub_1691 sugar ABC transporter; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Sugar ABC transporter; IMG reference gene:2504661538; PFAM: family.
 
    0.747
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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