STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11769.1KEGG: ttj:TTHA1726 S-layer repressor; SPTR: S-layer repressor; IMG reference gene:2504660616. (265 aa)    
Predicted Functional Partners:
AEB11768.1
Uncharacterized protein family UPF0310; COGs: COG2947 conserved hypothetical protein; InterPro IPR002740; KEGG: opr:Ocepr_0891 hypothetical protein; PFAM: Protein of unknown function DUF55; SPTR: Putative uncharacterized protein; IMG reference gene:2504660615; PFAM: Protein of unknown function DUF55.
       0.664
AEB11770.1
InterPro IPR003735; PFAM: Protein of unknown function DUF156; IMG reference gene:2504660617; PFAM: Uncharacterised BCR, COG1937.
       0.555
AEB11771.1
FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076; KEGG: cwo:Cwoe_2871 monooxygenase FAD-binding protein; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase FAD-binding protein; IMG reference gene:2504660618; PFAM: FAD binding domain.
       0.487
AEB11772.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR013027; KEGG: mac:MA0747 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Putative uncharacterized protein; IMG reference gene:2504660619; PFAM: HI0933-like protein.
       0.480
AEB11774.1
Phosphonate-transporting ATPase; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: afu:AF1819 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504660621; PFAM: ABC transporter.
  
    0.473
AEB11773.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: rmr:Rmar_1381 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; IMG reference gene:2504660620; PFAM: Methyltransferase domain.
       0.472
AEB11775.1
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: slp:Slip_1528 protein of unknown function DUF214; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Putative uncharacterized protein; IMG reference gene:2504660622; PFAM: Predicted permease.
       0.472
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.436
AEB11766.1
6-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR004849:IPR006115:IPR006114; KEGG: msv:Mesil_2478 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; 6-phosphogluconate dehydrogenase, C-terminal; PRIAM: Phosphogluconate dehydrogenase (decarboxylating); SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase-related protein; IMG reference gene:2504660613; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphoglucona [...]
       0.415
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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