STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11789.1Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: tth:TTC0378 hypothetical protein; PFAM: Secretion protein HlyD; SPTR: Hypothetical membrane spanning protein; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504660636; PFAM: HlyD family secretion protein. (398 aa)    
Predicted Functional Partners:
AEB11788.1
Outer membrane efflux protein; InterPro IPR003423; KEGG: ttj:TTHA0731 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660635; PFAM: Outer membrane efflux protein.
  
 
 0.951
AEB11787.1
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: ttj:TTHA0732 hypothetical protein; PFAM: Outer membrane efflux protein; SPTR: Putative uncharacterized protein TTHA0732; IMG reference gene:2504660634; PFAM: Outer membrane efflux protein.
  
 
 0.950
AEB11790.1
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: tth:TTC0377 acriflavin resistance protein B; PFAM: Acriflavin resistance protein; SPTR: Acriflavin resistance protein; IMG reference gene:2504660637; PFAM: AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.933
AEB11786.1
Regulatory protein MarR; InterPro IPR000835; KEGG: tth:TTC0381 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504660633; PFAM: MarR family.
  
  
 0.811
AEB10832.1
KEGG: msv:Mesil_2944 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504659636; PFAM: Outer membrane efflux protein.
  
 
 0.764
hisI
Phosphoribosyl-ATP pyrophosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR002496:IPR021130:IPR023019:IPR008179; KEGG: opr:Ocepr_1300 phosphoribosyl-amp cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG referenc [...]
  
    0.588
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
    0.536
AEB11780.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760; KEGG: msv:Mesil_1534 inositol monophosphatase; PFAM: Inositol monophosphatase; SPTR: Inositol monophosphatase; IMG reference gene:2504660627; PFAM: Inositol monophosphatase family.
     
 0.514
AEB12015.1
Hypothetical protein; COGs: COG5496 thioesterase; KEGG: ttj:TTHA0967 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660869.
  
     0.501
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.488
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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