STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11867.1Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: opr:Ocepr_1198 hypothetical protein; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: Probable hemolysin-related protein/CBS domain containing protein; IMG reference gene:2504660717; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain. (462 aa)    
Predicted Functional Partners:
ybeY
Metalloprotease ybeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.860
AEB11866.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.830
AEB11870.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: opr:Ocepr_1195 PhoH family protein; PFAM: PhoH-like protein; SPTR: PhoH family protein; IMG reference gene:2504660720; PFAM: PhoH-like protein.
  
  
 0.769
AEB11868.1
COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: mrb:Mrub_1813 diacylglycerol kinase; PFAM: Diacylglycerol kinase, prokaryotic; SPTR: Diacylglycerol kinase; IMG reference gene:2504660718; PFAM: Prokaryotic diacylglycerol kinase.
       0.729
AEB11872.1
UPF0365 protein; COGs: COG4864 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0365; InterPro IPR022853; KEGG: opr:Ocepr_1193 band 7 protein; SPTR: UPF0365 protein TaqDRAFT_3878; IMG reference gene:2504660722; PFAM: SigmaW regulon antibacterial.
       0.567
AEB11873.1
Protein of unknown function DUF107; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: opr:Ocepr_1192 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative protease/transporter; manually curated; IMG reference gene:2504660723; PFAM: Clp protease; NfeD-like.
       0.567
AEB11871.1
KEGG: mrb:Mrub_1816 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660721.
       0.566
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.545
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.445
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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