STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB11944.1Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: opr:Ocepr_1105 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; IMG reference gene:2504660798; PFAM: Metallo-beta-lactamase superfamily. (280 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.795
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.795
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
      0.727
AEB11270.1
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR004099; KEGG: opr:Ocepr_2051 fad-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: CoA-disulfide reductase; SPTR: NADH oxidase; IMG reference gene:2504660102; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
   
 0.510
AEB11945.1
TPR repeat-containing protein; InterPro IPR019734:IPR011717; KEGG: msv:Mesil_1008 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; IMG reference gene:2504660799; PFAM: LppC putative lipoprotein.
       0.499
AEB11941.1
Hypothetical protein; IMG reference gene:2504660795.
       0.488
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.