STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12050.1COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005846:IPR005843; KEGG: msv:Mesil_1936 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; IMG reference gene:2504660910; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Ph [...] (465 aa)    
Predicted Functional Partners:
AEB12556.1
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017472:IPR017475; KEGG: opr:Ocepr_2161 undecaprenyl-phosphate galactose phosphotransferase, wbap; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504661437; [...]
  
  
 0.664
AEB12390.1
D,D-heptose 1,7-bisphosphate phosphatase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterProIPR005835:IPR005834:IPR004446:IPR006543:IPR 006549; KEGG: msv:Mesil_0238 D,D-heptose 1,7-bisphosphate phosphatase; PFAM: Nucleotidyl transferase; Haloacid dehalogenase-like hydrolase; SPTR: D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamil [...]
  
  
 0.609
dacA
Conserved hypothetical protein CHP00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.606
AEB12046.1
KEGG: mrb:Mrub_1221 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660906.
     
 0.580
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
    
 0.574
AEB12045.1
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: msv:Mesil_2155 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol-phosphate synthase; IMG reference gene:2504660905; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
     
 0.574
AEB12049.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase.
       0.573
AEB12047.1
YbaK/prolyl-tRNA synthetase associated region; COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: tth:TTC1335 EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase-associated domain; SPTR: EbsC protein; IMG reference gene:2504660907; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein.
       0.572
AEB12048.1
KEGG: msv:Mesil_1938 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504660908.
       0.560
AEB11978.1
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: opr:Ocepr_1150 polynucleotide adenylyltransferase region; PFAM: Poly A polymerase, head domain; Cystathionine beta-synthase, core; Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SMART: Cystathionine beta-synthase, core; SPTR: Polynucleotide adenylyltransferase region; IMG reference gene:2504660832; PFAM: DHHA1 domain; DHH family; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) [...]
 
   
 0.509
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.