STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEB12071.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: opr:Ocepr_1242 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family; IMG reference gene:2504660931; PFAM: Response regulator rec [...] (192 aa)    
Predicted Functional Partners:
AEB12070.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_1241 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504660930; PFAM: HAMP domain; Histidine kinase-, DNA g [...]
 
 
 0.909
AEB11109.1
Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: opr:Ocepr_0428 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; SPTR: Histidine kinase; IMG reference gene:2504659931; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.877
AEB11334.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: opr:Ocepr_1841 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504660171; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.860
AEB12155.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: opr:Ocepr_1436 signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504661020; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.838
AEB11303.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_0564 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase; IMG reference gene:2504660138; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like [...]
 
 
 0.685
AEB12190.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: msv:Mesil_0931 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein; IMG reference gene:2504661058; PFAM: Response regulator receiver domain.
  
 
 0.678
AEB10887.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_2201 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504659691; PFAM: HAMP domain; Hist [...]
 
 
 0.669
AEB12412.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_1582 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Sensor histidine kinase; IMG reference gene:2504661286; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP9 [...]
 
 0.649
AEB10781.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_2124 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504659579; PFAM: HAMP domain; Hist [...]
 
 
 0.635
AEB12027.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR013655:IPR013767:IPR003018:IPR000160:IPR 001633:IPR000014:IPR001610; KEGG: aae:aq_1442 hypothetical protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; PAS fold-3; PAS fold; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; GAF; PAS; PAC motif; SPTR: Putative uncharacterized protein; TIGRFAM: PAS; Diguanylate cyclase, predicted; IMG ref [...]
  
 
 0.631
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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