STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AEB12214.1KEGG: opr:Ocepr_1303 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504661082; PFAM: Protein of unknown function (DUF3048). (674 aa)    
Predicted Functional Partners:
COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: opr:Ocepr_1304 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; IMG reference gene:2504661083; PFAM: Biopolymer transport protein ExbD/TolR.
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: opr:Ocepr_1305 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; IMG reference gene:2504661084; PFAM: MotA/TolQ/ExbB proton channel family.
Cell division protein FtsK/SpoIIIE; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: opr:Ocepr_1031 cell division protein FtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase FtsK gamma; SMART: DNA translocase FtsK gamma; ATPase, AAA+ type, core; SPTR: Cell division FtsK/SpoIIIE; IMG reference gene:2504660962; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Belongs to the FtsK/SpoIIIE/SftA family.
Protein of unknown function DUF255; COGs: COG1331 Highly conserved protein containing a thioredoxin domain; InterPro IPR004879:IPR010819; KEGG: msv:Mesil_1723 protein of unknown function DUF255; SPTR: Putative uncharacterized protein; IMG reference gene:2504660472; PFAM: Protein of unknown function, DUF255.
KEGG: msv:Mesil_2718 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504661085.
Putative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
VanW family protein; COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: opr:Ocepr_0245 VanW family protein; PFAM: Vancomycin resistance VanW; SPTR: VanW family protein; IMG reference gene:2504659724; PFAM: VanW like protein.
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000601:IPR000209:IPR022409; KEGG: opr:Ocepr_1550 peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; PKD domain; SMART: PKD/Chitinase domain; SPTR: Serine protease; IMG reference gene:2504661411; PFAM: Subtilase family.
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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