STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12274.1Protein of unknown function DUF59; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744; KEGG: ttj:TTHB138 hypothetical protein; PFAM: Domain of unknown function DUF59; SPTR: Putative uncharacterized protein TTHB138; IMG reference gene:2504661145; PFAM: Domain of unknown function DUF59. (109 aa)    
Predicted Functional Partners:
AEB12275.1
KEGG: msv:Mesil_0267 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504661146.
 
     0.809
AEB12626.1
FeS assembly ATPase SufC; COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR003593:IPR010230:IPR003439; KEGG: msv:Mesil_1007 FeS assembly ATPase SufC; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: FeS assembly ATPase SufC; TIGRFAM: ATPase SufC, SUF system FeS cluster assembly; IMG reference gene:2504661508; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
 
  
 0.621
AEB12276.1
Protein of unknown function DUF2249; COGs: COG4309 conserved hypothetical protein; InterPro IPR018720; KEGG: msv:Mesil_0266 protein of unknown function DUF2249; PFAM: Protein of unknown function DUF2249; SPTR: Putative uncharacterized protein; IMG reference gene:2504661147; PFAM: Uncharacterized conserved protein (DUF2249).
       0.559
AEB12631.1
SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: opr:Ocepr_1415 suf system fes assembly protein, NifU family; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; IMG reference gene:2504661513; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
  
    0.559
AEB12277.1
Domain of unknown function DUF1858; InterPro IPR015077; KEGG: sti:Sthe_0636 hypothetical protein; PFAM: Domain of unknown function DUF1858; SPTR: Putative uncharacterized protein; IMG reference gene:2504661148; PFAM: Uncharacterized conserved protein (DUF2249); Domain of unknown function (DUF1858).
       0.546
AEB12102.1
Phenylacetic acid degradation B; COGs: COG3460 Uncharacterized protein of phenylacetate metabolism; InterPro IPR009359; KEGG: sti:Sthe_2568 phenylacetic acid degradation B; PFAM: Phenylacetic acid degradation B; SPTR: Phenylacetic acid degradation B; IMG reference gene:2504660966; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit.
  
  
 0.533
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
     
 0.477
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.456
AEB12282.1
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: rmr:Rmar_2512 O-methyltransferase family 3; PFAM: O-methyltransferase, family 3; SPTR: Putative O-methyltransferase mdmC; IMG reference gene:2504661153; PFAM: O-methyltransferase.
       0.453
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.441
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.