STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12293.1Acylaminoacyl-peptidase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR001375; KEGG: msv:Mesil_1373 peptidase S9 prolyl oligopeptidase active site domain protein; PRIAM: Acylaminoacyl-peptidase; SPTR: Peptidase S9 prolyl oligopeptidase active site domain protein; IMG reference gene:2504661165; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat. (635 aa)    
Predicted Functional Partners:
AEB12295.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR013563:IPR010066:IPR003593; KEGG: msv:Mesil_1370 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; IMG reference gene:2504661167; [...]
 
    0.653
AEB12683.1
Glutamate carboxypeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: opr:Ocepr_0019 peptidase M20; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: Glutamate carboxypeptidase; SPTR: Carboxypeptidase G2; IMG reference gene:2504661567; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
     0.634
AEB12294.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR013563:IPR010066:IPR003593; KEGG: opr:Ocepr_0740 oligopeptide/dipeptide ABC transporter, atpase subunit; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide transport ATP-binding protein appF; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; IMG reference gene:250466116 [...]
 
    0.594
AEB12956.1
COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: tth:TTC0403 gamma-glutamyltranspeptidase; PFAM: Gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase superfamily; TIGRFAM: Gamma-glutamyltranspeptidase; IMG reference gene:2504661857; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase.
  
   
 0.563
menC
O-succinylbenzoic acid (OSB) synthetase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
 
     0.556
AEB12296.1
ABC-type transporter, integral membrane subunit; COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: opr:Ocepr_0738 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504661168; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.532
AEB12297.1
ABC-type transporter, integral membrane subunit; COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: opr:Ocepr_0737 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; IMG reference gene:2504661169; PFAM: Binding-protein-dependent transport system inner membrane component.
      0.525
AEB11843.1
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: msv:Mesil_1652 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Amidohydrolase 3; IMG reference gene:2504660692; PFAM: Amidohydrolase family.
 
     0.484
AEB12298.1
COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: opr:Ocepr_0736 extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Extracellular solute-binding protein family 5; IMG reference gene:2504661170; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
       0.474
AEB12524.1
Gcn5-related N-acetyltransferase; COGs: COG3375 conserved hypothetical protein; KEGG: opr:Ocepr_1699 gcn5-related N-acetyltransferase; SPTR: Putative uncharacterized protein TTHA0873; IMG reference gene:2504661401.
 
     0.456
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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