STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12421.1Agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: ttj:TTHA1129 agmatinase (SpeB); PFAM: Ureohydrolase; PRIAM: Agmatinase; SPTR: Agmatinase (SpeB); TIGRFAM: Putative agmatinase; IMG reference gene:2504661295; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family. (290 aa)    
Predicted Functional Partners:
argD
COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: opr:Ocepr_1059 acetylornithine aminotransferase apoenzyme; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Ornithine aminotransferase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; IMG reference gene:2504660754; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase famil [...]
  
 0.935
AEB10975.1
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: opr:Ocepr_0356 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; IMG reference gene:2504659785; PFAM: Carbon-nitrogen hydrolase.
  
 0.934
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 
 0.932
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
  
 
 0.922
AEB12422.1
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.777
hutH
COGs: COG2986 Histidine ammonia-lyase; HAMAP: Histidine ammonia-lyase; InterPro IPR005921:IPR001106; KEGG: msv:Mesil_1637 histidine ammonia-lyase; PFAM: Phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: Histidine ammonia-lyase; IMG reference gene:2504660595; PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase.
  
  
 0.616
AEB12420.1
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
       0.552
AEB12418.1
InterPro IPR002541; KEGG: opr:Ocepr_1587 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein-related protein; IMG reference gene:2504661292; PFAM: Cytochrome C assembly protein.
 
     0.537
AEB11322.1
Protein of unknown function DUF1385; COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: opr:Ocepr_1844 hypothetical protein; PFAM: Protein of unknown function DUF1385; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504660157; PFAM: Protein of unknown function (DUF1385).
   
    0.531
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
    0.483
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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