node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEB12049.1 | mfd | Marky_1312 | Marky_1239 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.442 |
AEB12049.1 | recA | Marky_1312 | Marky_0337 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.899 |
AEB12049.1 | thrS | Marky_1312 | Marky_1504 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.547 |
AEB12049.1 | uvrA | Marky_1312 | Marky_1886 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.622 |
AEB12049.1 | uvrB | Marky_1312 | Marky_0136 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.966 |
AEB12049.1 | uvrC | Marky_1312 | Marky_0763 | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.809 |
AEB12616.1 | AEB12620.1 | Marky_1885 | Marky_1889 | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | 0.611 |
AEB12616.1 | proA | Marky_1885 | Marky_1888 | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.602 |
AEB12616.1 | proB | Marky_1885 | Marky_1887 | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.629 |
AEB12616.1 | uvrA | Marky_1885 | Marky_1886 | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.664 |
AEB12620.1 | AEB12616.1 | Marky_1889 | Marky_1885 | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | 0.611 |
AEB12620.1 | proA | Marky_1889 | Marky_1888 | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.788 |
AEB12620.1 | proB | Marky_1889 | Marky_1887 | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.754 |
AEB12620.1 | uvrA | Marky_1889 | Marky_1886 | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.718 |
mfd | AEB12049.1 | Marky_1239 | Marky_1312 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: opr:Ocepr_1221 ATP-dependent DNA helicase, rep family; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase; IMG reference gene:2504660909; PFAM: UvrD/REP helicase. | 0.442 |
mfd | uvrA | Marky_1239 | Marky_1886 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.930 |
mfd | uvrB | Marky_1239 | Marky_0136 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.406 |
mfd | uvrC | Marky_1239 | Marky_0763 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.423 |
proA | AEB12616.1 | Marky_1888 | Marky_1885 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Tetratricopeptide TPR_2 repeat-containing protein; InterPro IPR019734:IPR001440:IPR013105; KEGG: opr:Ocepr_2153 tetratricopeptide tpr_1 repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_2 repeat protein; IMG reference gene:2504661498. | 0.602 |
proA | AEB12620.1 | Marky_1888 | Marky_1889 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR004664; KEGG: opr:Ocepr_1405 ribonuclease bn; PFAM: Ribonuclease BN-related; SPTR: Putative uncharacterized protein TTHA1929; IMG reference gene:2504661502; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). | 0.788 |