STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB12675.1Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: tra:Trad_0791 winged helix family two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; IMG r [...] (221 aa)    
Predicted Functional Partners:
AEB12674.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR003660; KEGG: tra:Trad_0687 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504661558; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.969
AEB11304.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: opr:Ocepr_0563 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two component transcriptional regulator, winged helix family; IMG [...]
  
  
 
0.919
AEB11005.1
COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_0548 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Phosphate regulon sensor protein phoR; IMG reference gene:2504659815; PFAM: HAMP domain; Histidine kinase-, DNA gyras [...]
 
 
 0.877
AEB12412.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_1582 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Sensor histidine kinase; IMG reference gene:2504661286; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP9 [...]
 
 
 0.871
AEB10781.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_2124 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504659579; PFAM: HAMP domain; Hist [...]
 
 0.869
AEB11303.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_0564 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Histidine kinase; IMG reference gene:2504660138; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like [...]
 
 
 0.869
AEB10887.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_2201 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504659691; PFAM: HAMP domain; Hist [...]
 
 
 0.868
AEB12070.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594; KEGG: opr:Ocepr_1241 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; IMG reference gene:2504660930; PFAM: HAMP domain; Histidine kinase-, DNA g [...]
 
 
 0.867
AEB11341.1
COGs: COG5002 Signal transduction histidine kinase; InterPro IPR013767:IPR003661:IPR003594:IPR000014; KEGG: mrb:Mrub_1540 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS; SPTR: PAS/PAC sensor signal transduction histidine kinase; IMG reference gene:2504660178; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPa [...]
 
 
 0.779
AEB12676.1
Hypothetical protein; KEGG: bwe:BcerKBAB4_5427 ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2504661560.
       0.723
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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