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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12735.1NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: mrb:Mrub_0065 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; IMG reference gene:2504661622; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. (157 aa)    
Predicted Functional Partners:
AEB12734.1
InterPro IPR005834; KEGG: hsl:OE1668R hypothetical protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Putative uncharacterized protein; IMG reference gene:2504661621.
       0.542
AEB10934.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...]
  
  
 0.417
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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