STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12742.1Heavy metal transport/detoxification protein; COGs: COG2608 Copper chaperone; InterPro IPR006121; KEGG: hth:HTH_1325 mercuric reductase; PFAM: Heavy metal transport/detoxification protein; SPTR: Mercuric reductase; IMG reference gene:2504661629; PFAM: Heavy-metal-associated domain. (69 aa)    
Predicted Functional Partners:
AEB11104.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.867
AEB12743.1
Mercuric reductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR021179:IPR013027:IPR004099; KEGG: msv:Mesil_1148 mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Mercury(II) reductase; SPTR: Mercuric reductase; TIGRFAM: Mercury reductase, MerA; IMG reference gene:2504661630; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase.
     
 0.786
AEB12744.1
KEGG: msv:Mesil_1147 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504661631.
       0.773
AEB12747.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: hla:Hlac_2992 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504661634; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: di [...]
     
 0.756
AEB12746.1
InterPro IPR003834; KEGG: ttr:Tter_2362 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; SPTR: Cytochrome c biogenesis protein transmembrane region; IMG reference gene:2504661633; PFAM: Cytochrome C biogenesis protein transmembrane region.
       0.749
AEB12745.1
Redoxin domain protein; InterPro IPR013740; KEGG: ckn:Calkro_0817 alkyl hydroperoxide reductase/thiol specific antioxidant/mal allergen; PFAM: Redoxin; SPTR: Redoxin domain protein; IMG reference gene:2504661632; PFAM: Redoxin.
       0.747
AEB12748.1
WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR019781; KEGG: scl:sce2686 WD repeat-containing protein; PFAM: WD40 repeat, subgroup; SPTR: Hypothetical WD-repeat protein; IMG reference gene:2504661635; PFAM: WD domain, G-beta repeat.
  
    0.744
AEB12749.1
Alkylmercury lyase; InterPro IPR004927; KEGG: xau:Xaut_0797 mercuric reductase; PFAM: Alkylmercury lyase; SPTR: Mercuric reductase; IMG reference gene:2504661636; PFAM: Alkylmercury lyase.
     
 0.684
AEB11155.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006404:IPR 006416:IPR001757; KEGG: dge:Dgeo_2581 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG [...]
  
 
 0.589
AEB11301.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR008250:IPR005834:IPR006403:IPR 006416:IPR001757; KEGG: hla:Hlac_2990 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:25 [...]
  
 
 0.589
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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