STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12748.1WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR019781; KEGG: scl:sce2686 WD repeat-containing protein; PFAM: WD40 repeat, subgroup; SPTR: Hypothetical WD-repeat protein; IMG reference gene:2504661635; PFAM: WD domain, G-beta repeat. (316 aa)    
Predicted Functional Partners:
AEB10934.1
ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR004589:IPR006055:IPR014001:IPR006554:IPR 006555:IPR001650:IPR013520:IPR006935:IPR011545; KEGG: msv:Mesil_3363 hypothetical protein; PFAM: Helicase, C-terminal; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Exonuclease, RNase T/DNA polymerase III; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: Exonuclease; DEAD-like helicase, N-terminal; Helicase-like, DEXD box c2 type; Helicase, ATP-dependent, c2 type; Helicase, C-terminal; SPTR: Putative uncharacterized protein [...]
 
 0.931
AEB11101.1
WD40 repeat-containing protein; COGs: COG2319 FOG: WD40 repeat; InterPro IPR019781:IPR001680; KEGG: ssl:SS1G_05532 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat; SPTR: WD-repeat protein, putative; IMG reference gene:2504659921; PFAM: WD domain, G-beta repeat; PEGA domain.
 
    
0.924
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.889
AEB11339.1
Beta-lactamase domain protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR001279:IPR011108; KEGG: opr:Ocepr_1840 RNA-metabolising metallo-beta-lactamase; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Beta-lactamase domain protein; IMG reference gene:2504660176; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain.
    
 0.875
AEB12811.1
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: tpe:Tpen_1284 ankyrin; PFAM: Ankyrin repeat; SPTR: Ankyrin; IMG reference gene:2504661705; PFAM: Ankyrin repeat.
  
 0.868
AEB11403.1
Metallophosphoesterase; InterPro IPR004843; KEGG: opr:Ocepr_1807 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2504660240.
   
 0.835
AEB12467.1
Metalloenzyme domain protein; InterPro IPR006124; KEGG: mrb:Mrub_1107 metalloenzyme domain-containing protein; PFAM: Metalloenzyme; SPTR: Metalloenzyme domain protein; IMG reference gene:2504661341; PFAM: Metalloenzyme superfamily.
   
 0.827
AEB12747.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: hla:Hlac_2992 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase; IMG reference gene:2504661634; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: di [...]
   
   0.785
AEB12745.1
Redoxin domain protein; InterPro IPR013740; KEGG: ckn:Calkro_0817 alkyl hydroperoxide reductase/thiol specific antioxidant/mal allergen; PFAM: Redoxin; SPTR: Redoxin domain protein; IMG reference gene:2504661632; PFAM: Redoxin.
       0.773
AEB12746.1
InterPro IPR003834; KEGG: ttr:Tter_2362 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; SPTR: Cytochrome c biogenesis protein transmembrane region; IMG reference gene:2504661633; PFAM: Cytochrome C biogenesis protein transmembrane region.
       0.773
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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