STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB12813.1Pseudouridine synthase Rsu; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR000748:IPR006145; KEGG: opr:Ocepr_2012 ribosomal large subunit pseudouridine synthase B; PFAM: RNA-binding S4; Pseudouridine synthase, RsuA and RluB/C/D/E/F; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; IMG reference gene:2504661707; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (240 aa)    
Predicted Functional Partners:
cmk
COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: opr:Ocepr_1777 cytidylate kinase; PFAM: Cytidylate kinase domain; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504660262; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
 
  
 0.908
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.834
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   
 0.810
AEB12812.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: msv:Mesil_3006 enoyl-CoA hydratase/isomerase; PFAM: Crotonase, core; SPTR: Enoyl-CoA hydratase/isomerase; IMG reference gene:2504661706; PFAM: Enoyl-CoA hydratase/isomerase family.
       0.774
AEB12811.1
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: tpe:Tpen_1284 ankyrin; PFAM: Ankyrin repeat; SPTR: Ankyrin; IMG reference gene:2504661705; PFAM: Ankyrin repeat.
       0.773
AEB12814.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: ttj:TTHA0220 hypoxanthine-guanine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504661708; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
    0.744
AEB12815.1
COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR004393:IPR022412:IPR002638; KEGG: ttj:TTHA0985 nicotinate-nucleotide pyrophosphorylase [carboxylating]; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal; PRIAM: Nicotinate-nucleotide diphosphorylase (carboxylating); SPTR: Nicotinate-nucleotide pyrophosphorylase; TIGRFAM: Nicotinate-nucleotide pyrophosphorylase; IMG reference gene:2504661709; PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-termina [...]
       0.718
nadA
Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.685
AEB12817.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.657
AEB11708.1
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
 
  
 0.639
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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