STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AEB12843.1MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: opr:Ocepr_0524 MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: MazG family protein; TIGRFAM: NTP pyrophosphohydrolase MazG, bacterial; IMG reference gene:2504661738; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. (198 aa)    
Predicted Functional Partners:
Prepilin peptidase; COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627:IPR000045; KEGG: opr:Ocepr_0525 prepilin peptidase; PFAM: Peptidase A24A, N-terminal; Peptidase A24A, prepilin type IV; PRIAM: Prepilin peptidase; SPTR: Peptidase A24A domain protein; IMG reference gene:2504661739; PFAM: Bacterial Peptidase A24 N-terminal domain; Type IV leader peptidase family.
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
NUDIX hydrolase; InterPro IPR000086; KEGG: opr:Ocepr_0523 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase; IMG reference gene:2504661737; PFAM: NUDIX domain.
Uncharacterized peroxidase-related enzyme; COGs: COG2128 conserved hypothetical protein; InterPro IPR010195:IPR004675:IPR003779; KEGG: sru:SRU_2769 peroxidase-related protein; PFAM: Carboxymuconolactone decarboxylase; SPTR: Uncharacterized peroxidase-related enzyme subfamily; TIGRFAM: Uncharacterised peroxidase-related; Alkylhydroperoxidase AhpD core; IMG reference gene:2504661736; PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: uncharacterized peroxidase-related enzyme; alkylhydroperoxidase AhpD family core domain.
KEGG: ttj:TTHA1168 hypothetical protein; SPTR: Putative uncharacterized protein TTHA1168; IMG reference gene:2504661740.
GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterProIPR002547:IPR005146:IPR005147:IPR005121:IPR 004532; KEGG: opr:Ocepr_1546 phenylalanyl-tRNA synthetase beta subunit; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SMART: B3/B4 tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; [...]
DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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