STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AEB12865.1Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: opr:Ocepr_2042 transcriptional regulator, GntR family; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: GntR, C-terminal; HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504661762; PFAM: Bacterial regulatory proteins, gntR family; FCD domain. (224 aa)    
Predicted Functional Partners:
AEB12961.1
GntR domain protein; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sti:Sthe_0681 GntR domain protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; GntR, C-terminal; SPTR: GntR domain protein; IMG reference gene:2504661862; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.831
AEB12864.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872; KEGG: msv:Mesil_3124 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; IMG reference gene:2504661761; PFAM: Proline dehydrogenase.
     
 0.821
AEB12863.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005932:IPR015590; KEGG: opr:Ocepr_2044 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; PRIAM: 1-pyrroline-5-carboxylate dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 2; IMG reference gene:2504661760; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative.
  
  
 0.798
AEB12866.1
TPR repeat-containing protein; COGs: COG2909 ATP-dependent transcriptional regulator protein; KEGG: msv:Mesil_2325 TPR repeat-containing protein; SPTR: TPR repeat-containing protein; IMG reference gene:2504661763.
       0.581
AEB11701.1
COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: ttj:TTHA1212 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504660546; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.
   
    0.539
AEB12862.1
COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: msv:Mesil_0115 peptidase M29 aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; IMG reference gene:2504661759; PFAM: Thermophilic metalloprotease (M29).
       0.512
AEB12868.1
o-succinylbenzoate--CoA ligase; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: tth:TTC0342 acyl-CoA ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: Acyl-CoA ligase; IMG reference gene:2504661765; PFAM: AMP-binding enzyme.
     
 0.447
AEB12872.1
Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: tth:TTC0338 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; IMG reference gene:2504661769; PFAM: Receptor family ligand binding region.
       0.445
AEB12873.1
ABC-type transporter, integral membrane subunit; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: tth:TTC0337 branched-chain amino acid transport system permease protein LivH; PFAM: ABC transporter permease; SPTR: Branched-chain amino acid transport system permease protein livH; IMG reference gene:2504661770; PFAM: Branched-chain amino acid transport system / permease component; Belongs to the binding-protein-dependent transport system permease family.
       0.445
AEB12874.1
ABC-type transporter, integral membrane subunit; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: mrb:Mrub_1677 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Inner-membrane translocator; IMG reference gene:2504661771; PFAM: Branched-chain amino acid transport system / permease component.
       0.444
Your Current Organism:
Marinithermus hydrothermalis
NCBI taxonomy Id: 869210
Other names: M. hydrothermalis DSM 14884, Marinithermus hydrothermalis DSM 14884, Marinithermus hydrothermalis T1, Marinithermus hydrothermalis str. DSM 14884, Marinithermus hydrothermalis strain DSM 14884
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