Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60289.1 | AEJ60291.1 | Spith_0002 | Spith_0004 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | 0.823 |
| AEJ60289.1 | AEJ60294.1 | Spith_0002 | Spith_0007 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.626 |
| AEJ60289.1 | AEJ60296.1 | Spith_0002 | Spith_0009 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Single-stranded nucleic acid binding R3H domain-containing protein; PFAM: R3H domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: sta:STHERM_c00090 hypothetical protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Single-stranded nucleic acid binding R3H domain-containing protein. | 0.647 |
| AEJ60289.1 | dnaA | Spith_0002 | Spith_0001 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.682 |
| AEJ60289.1 | gyrB | Spith_0002 | Spith_2296 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.665 |
| AEJ60289.1 | recF | Spith_0002 | Spith_0003 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.939 |
| AEJ60289.1 | recR | Spith_0002 | Spith_2278 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.484 |
| AEJ60289.1 | rnpA | Spith_0002 | Spith_0006 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.796 |
| AEJ60289.1 | rpmH | Spith_0002 | Spith_0005 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: sta:STHERM_c00060 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34. | 0.707 |
| AEJ60289.1 | yidC | Spith_0002 | Spith_0008 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.803 |
| AEJ60291.1 | AEJ60289.1 | Spith_0004 | Spith_0002 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.823 |
| AEJ60291.1 | AEJ60294.1 | Spith_0004 | Spith_0007 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.604 |
| AEJ60291.1 | AEJ60296.1 | Spith_0004 | Spith_0009 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | Single-stranded nucleic acid binding R3H domain-containing protein; PFAM: R3H domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: sta:STHERM_c00090 hypothetical protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Single-stranded nucleic acid binding R3H domain-containing protein. | 0.564 |
| AEJ60291.1 | dnaA | Spith_0004 | Spith_0001 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.448 |
| AEJ60291.1 | recF | Spith_0004 | Spith_0003 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.836 |
| AEJ60291.1 | rnpA | Spith_0004 | Spith_0006 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.612 |
| AEJ60291.1 | rpmH | Spith_0004 | Spith_0005 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; HAMAP: 50S ribosomal protein L34; InterPro IPR000271; KEGG: sta:STHERM_c00060 50S ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34. | 0.625 |
| AEJ60291.1 | yidC | Spith_0004 | Spith_0008 | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.584 |
| AEJ60294.1 | AEJ60289.1 | Spith_0007 | Spith_0002 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.626 |
| AEJ60294.1 | AEJ60291.1 | Spith_0007 | Spith_0004 | UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | PFAM: Protein of unknown function (DUF721); InterPro IPR007922; KEGG: sta:STHERM_c00040 hypothetical protein; PFAM: Protein of unknown function DUF721; SPTR: Putative uncharacterized protein. | 0.604 |
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