STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
AEJ60298.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: sta:STHERM_c00110 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; SPTR: Nucleo [...] (441 aa)    
Predicted Functional Partners:
AEJ60376.1
PFAM: Nucleotidyl transferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835; KEGG: sta:STHERM_c01020 hypothetical protein; PFAM: Nucleotidyl transferase; SPTR: UDP-glucose pyrophosphorylase.
 
 0.970
AEJ60337.1
PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sta:STHERM_c00500 protein CapI; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase.
 
 0.959
AEJ60643.1
UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886:IPR001509; KEGG: sta:STHERM_c03930 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-galactose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase.
  
 
 0.933
AEJ60450.1
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: sta:STHERM_c01790 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Mannose-1-phosphate guanylyltransferase.
 
 
 0.883
AEJ61868.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: sta:STHERM_c15620 transporter; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein.
  
  
 0.868
AEJ61882.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: cly:Celly_2621 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein.
  
  
 0.868
AEJ60647.1
PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR001937:IPR005849:IPR005850; KEGG: sta:STHERM_c03970 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, N-terminal; Galactose-1-phosphate uridyl transferase, C-terminal; SPTR: Galactose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class I.
    
 0.835
AEJ60896.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: sta:STHERM_c06020 hypothetical protein; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding; SPTR: Alcohol dehydrogenase GroES domain protein.
  
 
 0.817
uxaC
PFAM: Glucuronate isomerase; COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: sta:STHERM_c04600 uronate isomerase; PFAM: Uronate isomerase; SPTR: Uronate isomerase.
     
  0.800
fucI
L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
     
  0.800
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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