Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60302.1KEGG: sta:STHERM_c00150 hypothetical protein; SPTR: Putative uncharacterized protein. (540 aa)    
Predicted Functional Partners:
AEJ60301.1
Hypothetical protein; PFAM: DUF218 domain; KEGG: sta:STHERM_c00140 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ60427.1
KEGG: sta:STHERM_c01520 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.757
AEJ60386.1
KEGG: sta:STHERM_c01120 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.738
AEJ60429.1
KEGG: sta:STHERM_c01540 BNR domain-containing protein; SPTR: BNR domain-containing protein.
  
     0.736
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.636
AEJ60303.1
PFAM: Response regulator receiver domain; PAS fold; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: sta:STHERM_c00160 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
       0.623
AEJ60310.1
Transporter; PFAM: Sodium:dicarboxylate symporter family; COGs: COG1301 Na+/H+-dicarboxylate symporter; KEGG: sta:STHERM_c00230 transporter; SPTR: Putative uncharacterized protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
     0.601
lysA
Orn/DAP/Arg decarboxylase 2; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.584
AEJ61658.1
PFAM: FlaG protein; InterPro IPR005186; KEGG: sta:STHERM_c07720 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein.
  
     0.582
AEJ61022.1
KEGG: sta:STHERM_c14800 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.576
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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