STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
lysAOrn/DAP/Arg decarboxylase 2; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (419 aa)    
Predicted Functional Partners:
AEJ60848.1
PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048; KEGG: sta:STHERM_c05460 aspartokinase 3; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region.
   
 0.929
AEJ60568.1
PFAM: Saccharopine dehydrogenase; COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: sta:STHERM_c02980 saccharopine dehydrogenase; PFAM: Saccharopine dehydrogenase; SPTR: Carboxynorspermidine dehydrogenase.
  
 
 0.919
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
     
 0.912
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.871
AEJ62383.1
PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein; COGs: COG1509 Lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: sta:STHERM_c20840 L-lysine 2,3-aminomutase; PFAM: Radical SAM; SPTR: Lysine 2,3-aminomutase YodO family protein; TIGRFAM: Protein of unknown function DUF160.
     
 0.805
AEJ60340.1
Aspartate kinase; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR001341; KEGG: sta:STHERM_c00530 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region.
   
 0.726
AEJ60303.1
PFAM: Response regulator receiver domain; PAS fold; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: sta:STHERM_c00160 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
       0.723
dapL
LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
 
  
 0.605
AEJ60301.1
Hypothetical protein; PFAM: DUF218 domain; KEGG: sta:STHERM_c00140 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.584
AEJ60302.1
KEGG: sta:STHERM_c00150 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.584
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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