| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60317.1 | AEJ60318.1 | Spith_0030 | Spith_0031 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 0.636 |
| AEJ60317.1 | AEJ60319.1 | Spith_0030 | Spith_0032 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.655 |
| AEJ60317.1 | AEJ60320.1 | Spith_0030 | Spith_0033 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.636 |
| AEJ60317.1 | AEJ60321.1 | Spith_0030 | Spith_0034 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | PFAM: Glycosyl transferases group 1; InterPro IPR001296; KEGG: sta:STHERM_c00340 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1. | 0.475 |
| AEJ60317.1 | pfkA | Spith_0030 | Spith_0029 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.773 |
| AEJ60318.1 | AEJ60317.1 | Spith_0031 | Spith_0030 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.636 |
| AEJ60318.1 | AEJ60319.1 | Spith_0031 | Spith_0032 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.914 |
| AEJ60318.1 | AEJ60320.1 | Spith_0031 | Spith_0033 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.773 |
| AEJ60318.1 | AEJ60321.1 | Spith_0031 | Spith_0034 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | PFAM: Glycosyl transferases group 1; InterPro IPR001296; KEGG: sta:STHERM_c00340 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1. | 0.638 |
| AEJ60318.1 | AEJ61321.1 | Spith_0031 | Spith_1049 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit. | 0.414 |
| AEJ60318.1 | AEJ61447.1 | Spith_0031 | Spith_1175 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | PFAM: C4-dicarboxylate transporter/malic acid transport protein; TIGRFAM: C4-dicarboxylate transporter/malic acid transport protein; COGs: COG1275 Tellurite resistance protein and related permease; InterPro IPR004695; KEGG: mfe:Mefer_1360 C4-dicarboxylate transporter/malic acid transport protein; PFAM: C4-dicarboxylate transporter/malic acid transport protein; SPTR: C4-dicarboxylate transporter/malic acid transport protein. | 0.709 |
| AEJ60318.1 | AEJ61496.1 | Spith_0031 | Spith_1230 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | Hypothetical protein; PFAM: Alcohol acetyltransferase; KEGG: sta:STHERM_c11880 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.405 |
| AEJ60318.1 | pfkA | Spith_0031 | Spith_0029 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.636 |
| AEJ60319.1 | AEJ60317.1 | Spith_0032 | Spith_0030 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.655 |
| AEJ60319.1 | AEJ60318.1 | Spith_0032 | Spith_0031 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 0.914 |
| AEJ60319.1 | AEJ60320.1 | Spith_0032 | Spith_0033 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.773 |
| AEJ60319.1 | AEJ60321.1 | Spith_0032 | Spith_0034 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | PFAM: Glycosyl transferases group 1; InterPro IPR001296; KEGG: sta:STHERM_c00340 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1. | 0.557 |
| AEJ60319.1 | pfkA | Spith_0032 | Spith_0029 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.651 |
| AEJ60320.1 | AEJ60317.1 | Spith_0033 | Spith_0030 | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.636 |
| AEJ60320.1 | AEJ60318.1 | Spith_0033 | Spith_0031 | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 0.773 |