| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60315.1 | AEJ60317.1 | Spith_0028 | Spith_0030 | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.467 |
| AEJ60315.1 | AEJ60319.1 | Spith_0028 | Spith_0032 | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.685 |
| AEJ60315.1 | AEJ62094.1 | Spith_0028 | Spith_1835 | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c17640 acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.499 |
| AEJ60315.1 | pfkA | Spith_0028 | Spith_0029 | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.473 |
| AEJ60317.1 | AEJ60315.1 | Spith_0030 | Spith_0028 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | 0.467 |
| AEJ60317.1 | AEJ60318.1 | Spith_0030 | Spith_0031 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 0.636 |
| AEJ60317.1 | AEJ60319.1 | Spith_0030 | Spith_0032 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.657 |
| AEJ60317.1 | AEJ60320.1 | Spith_0030 | Spith_0033 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.636 |
| AEJ60317.1 | pfkA | Spith_0030 | Spith_0029 | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.773 |
| AEJ60318.1 | AEJ60317.1 | Spith_0031 | Spith_0030 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.636 |
| AEJ60318.1 | AEJ60319.1 | Spith_0031 | Spith_0032 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.914 |
| AEJ60318.1 | AEJ60320.1 | Spith_0031 | Spith_0033 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.773 |
| AEJ60318.1 | pfkA | Spith_0031 | Spith_0029 | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.636 |
| AEJ60319.1 | AEJ60315.1 | Spith_0032 | Spith_0028 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | Phosphatidate cytidylyltransferase; COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: sta:STHERM_c00280 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | 0.685 |
| AEJ60319.1 | AEJ60317.1 | Spith_0032 | Spith_0030 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | Metal dependent phosphohydrolase with GAF sensor; PFAM: HD domain; GAF domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: sta:STHERM_c00300 GAF domain/HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; GAF; SMART: GAF; Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase. | 0.657 |
| AEJ60319.1 | AEJ60318.1 | Spith_0032 | Spith_0031 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | Na+/glutamate symporter-like protein; COGs: COG0786 Na+/glutamate symporter; KEGG: sta:STHERM_c00310 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein. | 0.914 |
| AEJ60319.1 | AEJ60320.1 | Spith_0032 | Spith_0033 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | KEGG: sta:STHERM_c00330 hypothetical protein; SPTR: Flavodoxin. | 0.773 |
| AEJ60319.1 | AEJ61027.1 | Spith_0032 | Spith_0750 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | PFAM: 3-dehydroquinate synthase; COGs: COG0371 Glycerol dehydrogenase; InterPro IPR002658; KEGG: sta:STHERM_c14750 glycerol-1-phosphate dehydrogenase; PFAM: 3-dehydroquinate synthase AroB; SPTR: Glycerol-1-phosphate dehydrogenase (NAD(P)(+)). | 0.805 |
| AEJ60319.1 | AEJ61122.1 | Spith_0032 | Spith_0847 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | PFAM: Cytidylyltransferase family; COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: sta:STHERM_c13100 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase. | 0.914 |
| AEJ60319.1 | AEJ62094.1 | Spith_0032 | Spith_1835 | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c00320 hypothetical protein; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: sta:STHERM_c17640 acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. | 0.900 |