STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60326.1Carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: sta:STHERM_c00390 carboxy-terminal-processing protease precursor; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal protease. (488 aa)    
Predicted Functional Partners:
AEJ60327.1
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: sta:STHERM_c00400 automatic annotation; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047.
       0.780
AEJ60412.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c01370 lipoprotein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 
 0.761
AEJ60328.1
PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family; COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: sta:STHERM_c00410 glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF; SPTR: Glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: Glycosyl transferase WecB/TagA/CpsF.
     
 0.746
AEJ60329.1
PFAM: Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593; KEGG: sta:STHERM_c00420 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; SMART: ATPase, AAA+ type, core; SPTR: Sigma 54 interacting domain protein.
     
 0.694
AEJ60324.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c00370 flagellar synthesis regulator FleN; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN, putative.
 
     0.668
AEJ60323.1
PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c00360 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein.
       0.609
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.586
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
   0.564
AEJ60325.1
KEGG: sta:STHERM_c00380 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.559
AEJ62455.1
Biotin/lipoyl attachment domain-containing protein; PFAM: HMGL-like; Biotin-requiring enzyme; Conserved carboxylase domain; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR000089; KEGG: sta:STHERM_c21570 pyruvate carboxylase, beta chain; PFAM: Biotin/lipoyl attachment; Pyruvate carboxyltransferase; SPTR: Biotin/lipoyl attachment domain-containing protein.
  
    0.480
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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