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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEJ60329.1PFAM: Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593; KEGG: sta:STHERM_c00420 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; SMART: ATPase, AAA+ type, core; SPTR: Sigma 54 interacting domain protein. (378 aa)    
Predicted Functional Partners:
AEJ62495.1
RNA polymerase, sigma 54 subunit, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sta:STHERM_c21940 RNA polymerase sigma-54 factor; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigm [...]
 
   
 0.781
AEJ60328.1
PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family; COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: sta:STHERM_c00410 glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF; SPTR: Glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: Glycosyl transferase WecB/TagA/CpsF.
       0.773
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.726
AEJ60324.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c00370 flagellar synthesis regulator FleN; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN, putative.
  
 
 0.693
AEJ60326.1
Carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: sta:STHERM_c00390 carboxy-terminal-processing protease precursor; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: Carboxyl-terminal protease; TIGRFAM: Peptidase S41A, C-terminal protease.
       0.693
AEJ60327.1
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: sta:STHERM_c00400 automatic annotation; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047.
       0.693
AEJ60614.1
Multi-sensor signal transduction histidine kinase; PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR003594:IPR013767:IPR008207; KEGG: sta:STHERM_c03600 ammonia permease with sensory box/GGDEF domains; PFAM: Ammonium transporter; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: Ammoni [...]
  
 
 0.579
AEJ60323.1
PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c00360 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein.
  
    0.566
AEJ60845.1
Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: sta:STHERM_c05430 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; SMART: ATP-binding region, ATPase-like; Signal transduction histidine [...]
 
 
 0.558
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
  
 
 0.508
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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