Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60342.1Metal dependent phosphohydrolase; PFAM: HD domain; InterPro IPR006674:IPR006675; KEGG: sta:STHERM_c00550 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG. (360 aa)    
Predicted Functional Partners:
AEJ61892.1
PFAM: Poly A polymerase head domain; TIGRFAM: poly(A) polymerase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR010206:IPR002646; KEGG: sta:STHERM_c15790 polyA polymerase family protein; PFAM: Polynucleotide adenylyltransferase region; SPTR: Poly(A) polymerase; TIGRFAM: Poly(A) polymerase, PcnB.
 
  
 0.917
AEJ60343.1
KEGG: sta:STHERM_c00560 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.746
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
 
   0.501
AEJ60344.1
Hypothetical protein; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sta:STHERM_c00710 hypothetical protein; SPTR: Putative CDP-alcohol phosphatidyltransferase.
       0.494
AEJ60686.1
PFAM: Tetratricopeptide repeat; Protein of unknown function (DUF1570); InterPro IPR019734:IPR013105:IPR001440; KEGG: sta:STHERM_c04360 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.483
AEJ60345.1
PFAM: GtrA-like protein; KEGG: sta:STHERM_c00720 hypothetical protein; SPTR: GtrA family protein.
       0.482
AEJ60508.1
PFAM: Polysaccharide deacetylase; COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: sta:STHERM_c02380 polysaccharide deacetylase family protein; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase.
  
     0.407
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.407
AEJ62379.1
Hypothetical protein; PFAM: Hsp20/alpha crystallin family; KEGG: sta:STHERM_c20800 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the small heat shock protein (HSP20) family.
  
     0.404
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]